In a logistic regression analysis taking into account both the number of cardiovascular risk factors and CXCL4 levels, CXCL4 plasma levels were not associated with the diagnosis of CAD (HR 1.017, 95%-confidence interval 0.955–1.083, P = 0.596), whereas there was a significant association between the number of cardiovascular risk factors and CAD (HR 1.691, 95%-confidence interval 1.360–2.102, P<0.001). Here, PF4 is linked to coronary artery disorder.