Based on the evidence clearly suggesting a pro-atherogenic role for CXCL4 and the availability of novel imaging tools that allow detailed characterization of coronary atherosclerotic plaque composition such as coronary computed tomography angiography (CCTA) [18], we sought to determine whether CXCL4 levels are related with specific features of coronary artery disease including (1) plaque volume, (2) calcium score, (3) degree of stenosis, or (4) vascular remodeling. Here, PF4 is linked to coronary artery disorder.