For example, FGD/FGD-like conditions (MC2R, MRAP, NNT gene defects) can present with salt loss suggestive of adrenal hypoplasia, and alterations in STAR and CYP11A1 resulting in partial loss of protein function may have a predominant FGD-like phenotype (17, –, 20). The gene discussed is MRAP; the disease is chronic primary adrenal insufficiency.