TRIB1 and central nervous system cancer: The results showed that the Trib1 was detected in the human glioma cells, which was markedly up regulated by exposing to low doses (2 Gy/day for 1–4 days, or at graded doses for 4 days) irradiation in a time-dependent manner (Fig. 1A,B) and in an irradiation dose-dependent manner (Fig. 1C,D).