In a siRNA knockdown analysis of BCL6 in OCI-LY1 DLBCL cells [27], 104 of these lncRNAs were also seen to be upregulated (log2 fold change siBCL6/siNT >1) at 24 h time point BCL6 knockdown, while 48 of them are upregulated (log2 fold change siBCL6/siNT >1) at a 48 h time point knockdown of BCL6. As with EZH2, these numbers were significantly higher than expected by chance according to the hypergeometric test at 24 h (P <0.031) and 48 h time points (P <0.032). Here, EZH2 is linked to diffuse large B-cell lymphoma.