To determine if the SOBDA scores were responsive to changes in COPD status as measured by other COPD-related assessments (TDI, SGRQ, CAT, and trough FEV1), patients in the ITT population were defined as responders or non-responders according to these other assessments and the SOBDA change scores for these groups were examined. Here, CAT is linked to chronic obstructive pulmonary disease.