Syndecan-1 expression was not significantly different between patients with and without lymph node metastasis (random-effects model: OR = 0.91, 95 % CI = 0.34 − 2.43) or distant metastasis (random-effects model: OR = 0.89, 95 % CI = 0.19 − 4.21). The gene discussed is SDC1; the disease is metastatic malignant neoplasm in the lymph nodes.