This analysis revealed an inverse correlation in diabetic patients between serum level of TTP and the levels of IL-6 (correlation coefficient -0.572; R2 = 0.031; P<0.05) and IL-18 (correlation coefficient -0.685; R2 = 0.036; P<0.05) (Fig 3). This evidence concerns the gene IL18 and thrombotic thrombocytopenic purpura.