HOXB13 p.Gly84Glu mutation was not contributed to the development of breast cancer (OR = 1.423, 95% CI = 0.774−2.615, P = 0.256; Table 2) and colorectal cancer (OR = 2.458, 95% CI = 0.98−6.177, P = 0.056; Table 2) using fixed-effect models. Here, HOXB13 is linked to breast cancer.