TP53 and B-cell chronic lymphocytic leukemia: Thirdly, we showed that miR-3151 is a tumor suppressor miRNA in CLL, in contrast to recent reports that miR-3151 is oncogenic in cytogenetically normal acute myeloid leukemia (AML) [23, 24], in which miR-3151 functioned as the oncogenic driver targeting TP53 [25].