Firstly, the DIS3/BORA SAGP is significant and synergistic in terms of patients survival in two independent BC patients cohorts (Figure 4 and Supplementary file 1: Table S8); both gene partners are significantly correlated and activated in basal-like breast tumors (Supplementary file 3: Figure S1C and Supplementary file 3: Figure S1C). The gene discussed is DIS3; the disease is breast cancer.