The algorithm implementation identified the refined SAGPs-associated BC patients survival subgroups, which in turn led to the discovery of the 1381 SAGP-defined differentially expressed genes (DEGs) and GABPA transcriptionally co-activated gene network comprising many BC-relevant SAGPs, as well as certain specific gene sets involved in the cell cycle, proteasome and spliceosome pathways. The gene discussed is GABPA; the disease is breast cancer.