Although AKR1B10 was positively correlated with 14-3-3ε expression (p < 0.001), 14-3-3ε positive HCC patients with increased AKR1B10 expression paradoxically had better overall survival (Figure 4B) and progression-free survival (Figure 4C) rates as well as lower metastatic risks (Figure 4D). Here, AKR1B10 is linked to hepatocellular carcinoma.