Tumor-associated macrophages have been shown to possess features of the proinflammatory M1 phenotype in the early stages of tumorigenesis, but switch to an M2-like phenotype, with the acquisition of proangiogenic capability including the expression of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor [26] and MCP-1 [27]. Here, VEGFA is linked to neoplasm.