Finally, the last two biomedical SNP markers—rs587745372 and rs398048306—taken together are the well-known unique genetic variation in the TBP-binding site length, A (TA)5–8A in comparison with the norm: A (TA)7A. The longest of them, rs587745372, is an integral part of several haplotypes associated with a high risk of hyperbilirubinemia and jaundice [133], whereas two shortest ones, rs398048306 and rs200209906, are “silent SNPs” that are used to study ethnic differences of regional human subpopulations ([12] and Table 3). The gene discussed is TBP; the disease is Jaundice.