Transient elevation in serum ALT was observed in some subjects following 11 days’ single and multiple dosing with ceftazidime–avibactam in the CAZ-AVI PK part of the CAZ and AVI drug–drug interaction study; however, there were no concomitant elevations in other liver enzymes, and no clinical symptoms related to a liver disorder. The gene discussed is GPT; the disease is liver disorder.