ARG1 and androgen insensitivity syndrome: The purpose of this pilot study was to (1) examine the relationship between ARG1, NLR, and AIS severity; we hypothesized that increased ARG1 expression and serum protein activity is associated with an increased NLR, giving rise to increased AIS severity and poor outcome; (2) to validate the role of ARG1 as a novel biomarker of immune suppression in AIS; and (3) to utilize principal component analysis (PCA) to statistically model multiple gene expression changes following AIS.