Human stroke genomic biomarker studies have identified a common panel of five genes responding to AIS in the peripheral blood: arginase 1 (ARG1), lymphocyte antigen 96 (LY96), matrix metalloproteinase 9 (MMP9), s100 calcium-binding protein A12 (s100A12), and chemokine CC motif receptor 7 (CCR7) [5, 6]. Here, S100A12 is linked to Stroke.