DCTD and infection: At five (Fig 3a) and fifteen minutes (Fig 3b) post-infection, gene expression was observed almost exclusively on the right arm of the genome, which contains genes involved in DNA replication (DNA polymerase, DNA primases, DnaB-like helicases), integration (recombination endonuclease VII), nucleotide metabolism (deoxycytidylate deaminase, thymidylate synthase/thyX, ribonucleotide reductase, phosphoribosyl transferase), host immunity repression, and DNA methylation.