In comparison, the same concentration of celecoxib tested under comparable experimental conditions resulted in an upregulation of ICAM-1 protein level in lung cancer cells (A549, H460, lung cancer patient's metastatic cells) by up to 3.7- (Fig. 1A), 8- (Fig. 1B) or 6.3-fold (Fig. 1C) over control. Here, ICAM1 is linked to lung carcinoma.