This is an important distinction as previous cell biology work in fact predicted that high levels of UCH-L1 might facilitate proteasome inhibitor resistance [36], though this prior work was primarily performed in Burkitt lymphoma cells with high levels of MYC. In the myeloma datasets included here, there was no relationship between UCHL1 and MYC levels (data not shown). The gene discussed is MYC; the disease is Burkitt lymphoma.