BIRC5 and posterior cortical atrophy: We also conducted IHC staining in PCa tissue microarrays (TMAs) to detect the expression of survivin and p-STAT3 (Y705), and analysed their correlations with DAB2IP expression level reported in our previous studies.11 Indeed, we found that higher survivin expression was uniquely detected in high-grade or CPRC tissues and no survivin was detected in benign prostate tissues (Figure 6a), indicating its unique role as a proto-oncogene.