NEK2 and neoplasm: While GFP-Nek2 overexpression in shE2F3 cells did not modify tumor growth, an independent set of injections showed significant differences between shE2F3-GFP and GFP-Nek2, since GFP-Nek2 tumors were larger at early time points than shE2F3-GFP tumors (Figure 1).