NEK2 and neoplasm: In the shE2F3 group of shE2F3 vs shE2F;GFP-Nek2 pairs, two tumors (#7, 8) showed measurable necrosis (#7 with paramedical and comedo-like and #8 with central and comedo-like) para-medial in average 2.66 mm sq that represented average 8.96% of tumor area of all 5 mice.