MYCN and acute promyelocytic leukemia: Fucoxanthin is able to inhibit expression of the N-myc oncogene, cell cycle progression in human neuroblastoma cell lines, GOTO cells, N-ethyl-N′-nitro-N-nitrosoguanidine-induced mouse duodenal carcinogenesis, and the growth of human promyelocytic leukemia HL-60 cell by apoptosis induction [22].