Among the potential risk factors evaluated by univariate analysis, independent risk factors for AKI included age >65 years, decreased LVEF (quartile), preoperative sCr >1.2 mg/dL, serum albumin < 4.0 mg/dL, serum uric acid >5.5 mg/dL, large pRBC transfusions (quartile), platelet concentrate transfusion >8 units, intraoperative oliguria, highest intraoperative blood glucose >180 mg/dL, and N/L ratio (quartile) immediately postoperative and on POD one. The gene discussed is ALB; the disease is acute kidney injury.