The results showed that the pressure overload‐induced CH was significantly inhibited by celecoxib treatment characterized by decreasing HW/BW, HW/TL, cardiomyocytes size, as well as decreasing multiple hypertrophic markers expressions including ANP, BNP and β‐MHC in a time‐dependent manner (Fig. 4). Here, NPPA is linked to cyclic hematopoiesis.