In fact, the mitotic count and Ki67 staining of the NF1-GISTs were significantly lower than those of the other sporadic GISTs, and 5 NF1-GIST patients with R2 surgery had no evidence of recurrence at the time of analysis, with a median follow-up of 2.5 years. The gene discussed is MKI67; the disease is gastrointestinal stromal tumor.