SCARB1 and melanoma: In addition, we also probed individual, functional properties of the HDL NPs by testing if the blocking Ab targeting SR-B140; the small molecule inhibitor of free and esterified cholesterol flux through SR-B1, BLT-136; siRNA targeting melanoma cell SR-B1 expression; or combining HDL NPs and hHDL with BLT-1 would modulate cellular exosome uptake.