Immunohistochemistry-based morphoproteomic analysis showed constitutive activation of the c-MET pathway in the tumor cells to a mild degree, as evidenced by the expression of phosphorylated (p)-c-Met (Tyr1234/1235) in the cytoplasmic compartment (0 to 1+ with a rare 2+ chromogenic signal on a scale of 0 to 3+) (Figure 2). Here, MET is linked to neoplasm.