The expressions of both linc-POU3F3 and linc-H19 were significantly elevated in the CRC tissues compared with the adjacent non-tumor tissues (P < 0.01, Z = −3.684 for linc-POU3F3; P < 0.01, Z = − 3.805 for linc-H19; Fig. 1C, 1D). Here, POU3F3 is linked to neoplasm.