Genes essential for trafficking of lysosomal enzymes (Gnptab, Trim23, Trim30d, Vma21), transport of cargo through the golgi apparatus (Golim4, Golph3, Vps35, Synrg), endoplasmic reticulum (Sec13, Sec22a, Sec63) and general intracellular trafficking (Arcn1, Exosc1) were also modulated in presence of infection. The gene discussed is EXOSC1; the disease is infection.