CEACAM5 and colorectal carcinoma: Similar results were seen with a recombinant fowl pox virus expressing multiple co-stimulatory molecules (B7.1, LFA-3, ICAM-1) and the CEA antigen—administered alone or in sequence with a recombinant vaccinia virus expressing the same molecules—to patients with a variety of CEA-expressing tumors, including 35 patients with CRC.