The concentrations of plasma IL-10 were correlated positively with the percentages of circulating IL-10+CD14+CD169+ monocytes (R = 0.6018, P<0.0001; Fig 3H) and the levels of plasma CEA in the CRC patients (R = 0.413, P = 0.0043; Fig 3I). This evidence concerns the gene SIGLEC1 and colorectal carcinoma.