TNNT2 and cardiomyopathy: The implication for oxidative damage and antioxidant therapy in sarcomere protein-mutated cardiomyopathy was previously studied by Marian et al. who tested the effects of antioxidant N-acetylcysteine (NAC), a precursor of glutathione, on diminishing established interstitial fibrosis in a mouse model of human HCM caused by cTnT-Q92 mutation [8].