TNNT2 and familial dilated cardiomyopathy: cTnT-Q92 mice had elevated levels of myocardial MDA and 4-hydroxy-2(E)-nonenal (4HNE), similar to what we observed in cMyBP-C(t/t) DCM heart tissue homogenates (Figure 4(e)), which is indicative of lipid peroxidation and oxidative damage.