Similar to these reports, we observed significantly elevated fibrosis (Figures 1(h) and 1(j)), collagen deposition (Figures 2(b) and 2(c)), carbonyl content (Figure 4(d)), and MDA and HAE levels (Figure 4(e)) as well as a reduction in the GSH/GSSG ratio (Figure 4(c)) in cMyBP-C(t/t) DCM hearts and in heart tissue homogenates from cardiomyopathy patients (Figures 4(f)–4(h)), signifying increased myocardial damage and oxidative stress. Here, MYBPC3 is linked to familial dilated cardiomyopathy.