RHO and cancer: Numerous studies have thus far investigated the therapeutic efficacy of Rho/ROCK inhibition in in vitro and in vivo models of cancer (Table 1, (Refs 5, 28, 29, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58).