By using the same single microvessel perfusion method, our previous study10 reported that pretreatment of tumor cells with an antibody blocking VEGF or an antibody blocking a specific integrin, and pretreatment of the microvessel with VEGF receptor inhibitor, or anti-integrin extracellular matrix ligand antibody, can reduce the tumor cell adhesion under both control and the VEGF treatment. The gene discussed is VEGFA; the disease is neoplasm.