PER1 and Parkinson disease: Numerous imputed SNPs showed significant associations with PD (Fig. 2), including rs11022743 (P = 1.28 × 10−3), rs2279284 (P = 1.28 × 10−3) and rs4757137 (P = 1.26 × 10−3) in ARNTL and rs58356259 (P = 7.11 × 10−4) in PER1. Several of them were located in the enhancer or promoter region of ARNTL (Fig. 2).