CASP3 and central nervous system cancer: We observed that the expression of apoptosis-related factors (cleaved caspase 3 and Bad) was lower, while the expression of anti-apoptosis (Bcl2), invasion (MMP2 and MMP9) and chemokine pathway related factors (CXCL10 and CXCR3) was higher in glioma tissues than in normal tissues.