Furthermore, the association between TREM2 expression and prognosis in patients with gliomas was determined by analyzing our own data, as well as the TCGA GBM and GSE 16011 datasets [16] (http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-16011/?query=GSE16011). The gene discussed is TREM2; the disease is central nervous system cancer.