As shown in Figure 2, two TREM2 siRNAs (TREM2-siRNA-1 and TREM2-siRNA-2) were able to efficiently suppress endogenous TREM2 expression in both glioma cells, whereas TREM2 expression remained unaffected in control siRNA-transfected cells (NC). This evidence concerns the gene TREM2 and central nervous system cancer.