Inducible expression of IP10 has been demonstrated in monocytes, endothelial cells and fibroblasts [42,43] and regulates the reparative response in an experimental model of myocardial infarction [44] To our knowledge, no previous study reported on the functional effects of CXCR3 agonists on the response of the heart to hemodynamic overload. This evidence concerns the gene CXCR3 and myocardial infarction.