In our study we profiled expression of disease-associated lncRNAs in CRC tumor tissues and identified ZFAS1 (zinc finger antisense 1), previously observed to be tumor suppressor gene in human breast cancer [19, 20] and oncogene in hepatocellular carcinoma [21], to be up-regulated in CRC tissue. The gene discussed is ZFAS1; the disease is hepatocellular carcinoma.