For that, the authors analyzed the expression of BRMS1 protein and Cytokeratins 8, 18, and 19 by immunofluorescent staining on cytospin preparations of peripheral mononuclear cells (PBMNCs) enriched via Ficoll density gradient centrifugation from peripheral blood of patients with operable breast cancer. The gene discussed is BRMS1; the disease is breast carcinoma.