APOL1 and systemic lupus erythematosus: In a subsequent study, Freedman and colleagues genotyped the SNPs in APOL1 (rs73885319 and rs60910145 in G1 allele, and rs71785313 in G2 allele) in 855 African American SLE patients with end-stage renal disease (ESRD) and 534 African American SLE patients without renal involvement.