ERBB2 and breast cancer: This study confirmed the presence of high TILs as a robust favorable prognosticator in high-risk operable breast cancer, an effect that was more pronounced in HER2 positive and TNBC patients, in line with previous reports in the adjuvant [5, 7-9, 11, 24] and neoadjuvant setting [6, 9, 11, 13].