The single-marker analysis showed that five SNPs in the 3′-untranslated region of the NFAT5 gene were associated with cocaine dependence, and two of them (rs1437134 and rs7359336, in high linkage disequilibrium) survived the Bonferroni correction for multiple testing (Table 1; Supplementary Table 5; Supplementary Figure 3). Here, NFAT5 is linked to cocaine dependence.