At day 22, parasitemia levels of approximately 8.0% were seen for the naïve controls (8.07± 3.9%) and the MVA-CSP group (6.7± 4.3%) while the parasitemia was essentially cleared (0.01± 0.01%) for the MVA-CSP/IL15 vaccinated mice. The gene discussed is IL15; the disease is parasitic infectious disease.