Profound thrombocytopenia (<100.000) was observed in 2.5% of myocardial infarcts after abciximab and 0.5% after tirofiban treatment combined with PCI and dual oral antiplatelet agents and in 0.6% of patients treated by GPIIb/IIIa inhibitors according to the GRACE registry [8–10]. The gene discussed is ITGA2B; the disease is Thrombocytopenia.