Jiang et al. showed that miR-7 regulated IGF1R/IRS/PI3K/Akt signaling pathway by posttranscriptional regulation of insulin-like growth factor 1 receptor (IGF1R) in cells derived from tongue squamous cell carcinoma (TSCC, the most common subtype of OSCC) cells [45]. Here, IGF1R is linked to tongue squamous cell carcinoma.