In the present study, we aimed to evaluate the expression profiles of inflammatory cytokines and chemokine, including TNF-α, IL-6, IL-10, IL-18, IL-18 binding protein (IL-18BP), IL-23A, IL-27, IL-33, IL-37, and monocyte chemoattractant protein- (MCP-) 1 in peripheral blood mononuclear cells (PBMCs) of patients with either ACS or stable CAD. Here, IL27 is linked to coronary artery disorder.