First, we only explored the response of RSCs, not the differentiated mature neuroretinal cells to IL-1β, IL-18, and IL-17A; in future studies, we plan to differentiate the RSCs to photoreceptor cells and explore their response to these cytokines, which will be a better model for photoreceptor changes in AMD. The gene discussed is IL18; the disease is age-related macular degeneration.