We next asked whether rats fed a HFD for 26 weeks would develop NASH and, in this paper, we study the effects of soothing liver and invigorating spleen recipes on inflammatory markers and proteins involved in IKKβ-NF-κB p65 pathway in KCs to explore some of the underlying mechanisms involved. The gene discussed is NFKB1; the disease is metabolic dysfunction-associated steatohepatitis.