Finally, using matched tumour/normal exome sequencing data from our recent study of 42 UK TGCT patients25, we analysed somatic mutational events occurring in genes ATP1B3, BCAR4, GAB2, GSPT1, RSL1D1, TFDP2, TNFRSF17, USP35 and ZFPM1. The only recurring event, seen in >5% of tumours was a copy number deletion encompassing GAB2 and USP35 at 11q14.1 found in 7% of tumours. The gene discussed is USP35; the disease is neoplasm.