The results revealed that high IRAK1 expression positively correlated with reduced overall survival, distant metastasis-free survival and relapse-free survival ((P=0.0047, P=0.017 and P=2.1 × 106, respectively, Fig. 1c), suggesting a prognostic value of IRAK1 in breast cancers. This evidence concerns the gene IRAK1 and breast carcinoma.