Endogenous estrogens promote breast cancer by binding to estrogen receptor α (ERα) (Burns and Korach 2012; Sommer and Fuqua 2001), which causes the activation of oncogenes, such as c-Myc and cyclin D1 (Leygue et al. 1995; Liao and Dickson 2000). Here, ESR1 is linked to breast carcinoma.